One of the most commonly seen complications of contact lens wear is allergic conjunctivitis or Giant Papillary Conjunctivitis (GPC). This usually develops from wearing contact lenses longer than their prescribed use or wearing dirty contact lenses. The eye reacts to the dirty lens by developing papillae or bumps under the upper eyelid as seen in the photo below.
Contact lenses usually decenter frequently and cloud with a mucus discharge. The eye often feels itchy and scratchy when contact lens is removed and better with the lens on.
Treatment usually involves medication to treat the allergy and changing to a more frequent contact lens replacement schedule. People prone to GPC with contact lenses may need to change to daily replacement lenses.